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Pathogenesis of peroxisomal deficiency disorders (Zellweger syndrome) may be mediated by misregulation of the GABAergic system via the diazepam binding inhibitor

BACKGROUND: Zellweger syndrome (ZS) is a fatal inherited disease caused by peroxisome biogenesis deficiency. Patients are characterized by multiple disturbances of lipid metabolism, profound hypotonia and neonatal seizures, and distinct craniofacial malformations. Median live expectancy of ZS patien...

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Detalles Bibliográficos
Autor principal:	Breitling, Rainer
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC391370/ https://www.ncbi.nlm.nih.gov/pubmed/15102341 http://dx.doi.org/10.1186/1471-2431-4-5

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