Mycobacterium tuberculosis Cyclophilin A Uses Novel Signal Sequence for Secretion and Mimics Eukaryotic Cyclophilins for Interaction with Host Protein Repertoire

Cyclophilins are prolyl isomerases with multitude of functions in different cellular processes and pathological conditions. Cyclophilin A (PpiA) of Mycobacterium tuberculosis is secreted during infection in intraphagosomal niche. However, our understanding about the evolutionary origin, secretory me...

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Detalles Bibliográficos
Autores principales: Bhaduri, Asani, Misra, Richa, Maji, Abhijit, Bhetaria, Preetida J., Mishra, Sonakshi, Arora, Gunjan, Singh, Lalit Kumar, Dhasmana, Neha, Dubey, Neha, Virdi, Jugsharan Singh, Singh, Yogendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913756/
https://www.ncbi.nlm.nih.gov/pubmed/24505389
http://dx.doi.org/10.1371/journal.pone.0088090

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