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Induction of Specific Humoral and Cellular Immune Responses in a Mouse Model following Gene Fusion of HSP70C and Hantaan Virus Gn and S0.7 in an Adenoviral Vector

Heat shock proteins (HSPs) display adjuvant functions when given as fusion proteins to enhance vaccination efficiency. To evaluate enhanced potency of Hantaan virus (HTNV) glycoprotein (GP) and nucleocapsid protein (NP) immunogenicity by heat shock protein 70 (HSP70), a recombinant adenovirus rAd-Gn...

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Detalles Bibliográficos
Autores principales:	Cheng, Linfeng, Yu, Lan, Wu, Xingan, Li, Kai, Wang, Fang, Zhang, Liang, Ye, Wei, Li, Puyuan, Zhang, Fanglin, Xu, Zhikai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913774/ https://www.ncbi.nlm.nih.gov/pubmed/24505421 http://dx.doi.org/10.1371/journal.pone.0088183

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