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Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression

Prolactin controls the development and function of milk-producing breast epithelia but also supports growth and differentiation of breast cancer, especially luminal subtypes. A principal signaling mediator of prolactin, Stat5, promotes cellular differentiation of breast cancer cells in vitro, and lo...

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Detalles Bibliográficos
Autores principales: Sato, Takahiro, Tran, Thai H., Peck, Amy R., Girondo, Melanie A., Liu, Chengbao, Goodman, Chelain R., Neilson, Lynn M., Freydin, Boris, Chervoneva, Inna, Hyslop, Terry, Kovatich, Albert J., Hooke, Jeffrey A., Shriver, Craig D., Fuchs, Serge Y., Rui, Hallgeir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913798/
https://www.ncbi.nlm.nih.gov/pubmed/23708665
http://dx.doi.org/10.1038/onc.2013.172