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Digital-Direct-RT-PCR: a sensitive and specific method for quantification of CTC in patients with cervical carcinoma

The detection of circulating tumour cells (CTC) in cancer patients may be useful for therapy monitoring and prediction of relapse. A sensitive assay based on HPV-oncogene transcripts which are highly specific for cervical cancer cells was established. The Digital-Direct-RT-PCR (DD-RT-PCR) combines F...

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Detalles Bibliográficos
Autores principales: Pfitzner, Claudia, Schröder, Isabel, Scheungraber, Cornelia, Dogan, Askin, Runnebaum, Ingo Bernhard, Dürst, Matthias, Häfner, Norman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913920/
https://www.ncbi.nlm.nih.gov/pubmed/24496006
http://dx.doi.org/10.1038/srep03970