Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration

Background. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure. Case report. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed....

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Autores principales: Bourquin, Vincent, Ponte, Belén, Hirschel, Bernard, Pugin, Jérôme, Martin, Pierre-Yves, Saudan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914130/
https://www.ncbi.nlm.nih.gov/pubmed/24527237
http://dx.doi.org/10.1155/2011/817414
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author Bourquin, Vincent
Ponte, Belén
Hirschel, Bernard
Pugin, Jérôme
Martin, Pierre-Yves
Saudan, Patrick
author_facet Bourquin, Vincent
Ponte, Belén
Hirschel, Bernard
Pugin, Jérôme
Martin, Pierre-Yves
Saudan, Patrick
author_sort Bourquin, Vincent
collection PubMed
description Background. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure. Case report. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed. The expected mortality was estimated at 90% with clinical scores. The patient underwent plasma exchanges and high-volume hemofiltration (HVHF) with complete recovery of hepatic and kidney functions. Discussion. Plasma exchanges and HVHF may confer survival benefit on patients with severe leptospirosis, refractory septic shock, and multiple-organ failure.
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spelling pubmed-39141302014-02-13 Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration Bourquin, Vincent Ponte, Belén Hirschel, Bernard Pugin, Jérôme Martin, Pierre-Yves Saudan, Patrick Case Rep Nephrol Case Report Background. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure. Case report. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed. The expected mortality was estimated at 90% with clinical scores. The patient underwent plasma exchanges and high-volume hemofiltration (HVHF) with complete recovery of hepatic and kidney functions. Discussion. Plasma exchanges and HVHF may confer survival benefit on patients with severe leptospirosis, refractory septic shock, and multiple-organ failure. Hindawi Publishing Corporation 2011 2011-09-13 /pmc/articles/PMC3914130/ /pubmed/24527237 http://dx.doi.org/10.1155/2011/817414 Text en Copyright © 2011 Vincent Bourquin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bourquin, Vincent
Ponte, Belén
Hirschel, Bernard
Pugin, Jérôme
Martin, Pierre-Yves
Saudan, Patrick
Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration
title Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration
title_full Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration
title_fullStr Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration
title_full_unstemmed Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration
title_short Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration
title_sort severe leptospirosis with multiple organ failure successfully treated by plasma exchange and high-volume hemofiltration
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914130/
https://www.ncbi.nlm.nih.gov/pubmed/24527237
http://dx.doi.org/10.1155/2011/817414
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