The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure

The McKittrick-Wheelock syndrome is a rare cause of severe hydroelectrolyte disorders and fluid depletion as a result of rectal tumor hypersecretion, which can lead to acute renal failure. We report the case of a 70-year-old female who presented with hyponatremia, hypokalemia, hypochloremia, and acu...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruno, Andrea, Chimienti, Domenico, Montanaro, Alda, Prete, Fernando, Libutti, Pasquale, Lisi, Piero, Basile, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914135/
https://www.ncbi.nlm.nih.gov/pubmed/24533197
http://dx.doi.org/10.1155/2011/765689
_version_ 1782302352734158848
author Bruno, Andrea
Chimienti, Domenico
Montanaro, Alda
Prete, Fernando
Libutti, Pasquale
Lisi, Piero
Basile, Carlo
author_facet Bruno, Andrea
Chimienti, Domenico
Montanaro, Alda
Prete, Fernando
Libutti, Pasquale
Lisi, Piero
Basile, Carlo
author_sort Bruno, Andrea
collection PubMed
description The McKittrick-Wheelock syndrome is a rare cause of severe hydroelectrolyte disorders and fluid depletion as a result of rectal tumor hypersecretion, which can lead to acute renal failure. We report the case of a 70-year-old female who presented with hyponatremia, hypokalemia, hypochloremia, and acute renal failure, due to a watery, mucinous diarrhea. A large rectal villous adenoma was discovered on ileocolonoscopy, and definitive management was achieved by removal of the tumor. In conclusion, reversal of the biochemical derangement is the cornerstone of successful management of the McKittrick-Wheelock syndrome. Then, immediate surgical resection of the tumor is the treatment of choice.
format Online
Article
Text
id pubmed-3914135
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-39141352014-02-16 The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure Bruno, Andrea Chimienti, Domenico Montanaro, Alda Prete, Fernando Libutti, Pasquale Lisi, Piero Basile, Carlo Case Rep Nephrol Case Report The McKittrick-Wheelock syndrome is a rare cause of severe hydroelectrolyte disorders and fluid depletion as a result of rectal tumor hypersecretion, which can lead to acute renal failure. We report the case of a 70-year-old female who presented with hyponatremia, hypokalemia, hypochloremia, and acute renal failure, due to a watery, mucinous diarrhea. A large rectal villous adenoma was discovered on ileocolonoscopy, and definitive management was achieved by removal of the tumor. In conclusion, reversal of the biochemical derangement is the cornerstone of successful management of the McKittrick-Wheelock syndrome. Then, immediate surgical resection of the tumor is the treatment of choice. Hindawi Publishing Corporation 2011 2011-10-01 /pmc/articles/PMC3914135/ /pubmed/24533197 http://dx.doi.org/10.1155/2011/765689 Text en Copyright © 2011 Andrea Bruno et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bruno, Andrea
Chimienti, Domenico
Montanaro, Alda
Prete, Fernando
Libutti, Pasquale
Lisi, Piero
Basile, Carlo
The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure
title The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure
title_full The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure
title_fullStr The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure
title_full_unstemmed The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure
title_short The Mckittrick-Wheelock Syndrome: A Rare Cause of Severe Hydroelectrolyte Disorders and Acute Renal Failure
title_sort mckittrick-wheelock syndrome: a rare cause of severe hydroelectrolyte disorders and acute renal failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914135/
https://www.ncbi.nlm.nih.gov/pubmed/24533197
http://dx.doi.org/10.1155/2011/765689
work_keys_str_mv AT brunoandrea themckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT chimientidomenico themckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT montanaroalda themckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT pretefernando themckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT libuttipasquale themckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT lisipiero themckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT basilecarlo themckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT brunoandrea mckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT chimientidomenico mckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT montanaroalda mckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT pretefernando mckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT libuttipasquale mckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT lisipiero mckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure
AT basilecarlo mckittrickwheelocksyndromeararecauseofseverehydroelectrolytedisordersandacuterenalfailure

Ejemplares similares