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Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi

Background. Development of non-deqi control is still a challenge. This study aims to set up a potential approach to non-deqi control by using lidocaine anesthesia at ST36. Methods. Forty healthy volunteers were recruited and they received two fMRI scans. One was accompanied with manual acupuncture a...

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Autores principales: Jin, Ling-min, Qin, Cai-juan, Lan, Lei, Sun, Jin-bo, Zeng, Fang, Zhu, Yuan-qiang, Yu, Shu-guang, Yin, Hai-yan, Tang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914330/
https://www.ncbi.nlm.nih.gov/pubmed/24550995
http://dx.doi.org/10.1155/2014/987365
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author Jin, Ling-min
Qin, Cai-juan
Lan, Lei
Sun, Jin-bo
Zeng, Fang
Zhu, Yuan-qiang
Yu, Shu-guang
Yin, Hai-yan
Tang, Yong
author_facet Jin, Ling-min
Qin, Cai-juan
Lan, Lei
Sun, Jin-bo
Zeng, Fang
Zhu, Yuan-qiang
Yu, Shu-guang
Yin, Hai-yan
Tang, Yong
author_sort Jin, Ling-min
collection PubMed
description Background. Development of non-deqi control is still a challenge. This study aims to set up a potential approach to non-deqi control by using lidocaine anesthesia at ST36. Methods. Forty healthy volunteers were recruited and they received two fMRI scans. One was accompanied with manual acupuncture at ST36 (DQ group), and another was associated with both local anesthesia and manual acupuncture at the same acupoint (LA group). Results. Comparing to DQ group, more than 90 percent deqi sensations were reduced by local anesthesia in LA group. The mainly activated regions in DQ group were bilateral IFG, S1, primary motor cortex, IPL, thalamus, insula, claustrum, cingulate gyrus, putamen, superior temporal gyrus, and cerebellum. Surprisingly only cerebellum showed significant activation in LA group. Compared to the two groups, bilateral S1, insula, ipsilateral IFG, IPL, claustrum, and contralateral ACC were remarkably activated. Conclusions. Local anesthesia at ST36 is able to block most of the deqi feelings and inhibit brain responses to deqi, which would be developed into a potential approach for non-deqi control. Bilateral S1, insula, ipsilateral IFG, IPL, claustrum, and contralateral ACC might be the key brain regions responding to deqi.
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spelling pubmed-39143302014-02-18 Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi Jin, Ling-min Qin, Cai-juan Lan, Lei Sun, Jin-bo Zeng, Fang Zhu, Yuan-qiang Yu, Shu-guang Yin, Hai-yan Tang, Yong Evid Based Complement Alternat Med Research Article Background. Development of non-deqi control is still a challenge. This study aims to set up a potential approach to non-deqi control by using lidocaine anesthesia at ST36. Methods. Forty healthy volunteers were recruited and they received two fMRI scans. One was accompanied with manual acupuncture at ST36 (DQ group), and another was associated with both local anesthesia and manual acupuncture at the same acupoint (LA group). Results. Comparing to DQ group, more than 90 percent deqi sensations were reduced by local anesthesia in LA group. The mainly activated regions in DQ group were bilateral IFG, S1, primary motor cortex, IPL, thalamus, insula, claustrum, cingulate gyrus, putamen, superior temporal gyrus, and cerebellum. Surprisingly only cerebellum showed significant activation in LA group. Compared to the two groups, bilateral S1, insula, ipsilateral IFG, IPL, claustrum, and contralateral ACC were remarkably activated. Conclusions. Local anesthesia at ST36 is able to block most of the deqi feelings and inhibit brain responses to deqi, which would be developed into a potential approach for non-deqi control. Bilateral S1, insula, ipsilateral IFG, IPL, claustrum, and contralateral ACC might be the key brain regions responding to deqi. Hindawi Publishing Corporation 2014 2014-01-16 /pmc/articles/PMC3914330/ /pubmed/24550995 http://dx.doi.org/10.1155/2014/987365 Text en Copyright © 2014 Ling-min Jin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Jin, Ling-min
Qin, Cai-juan
Lan, Lei
Sun, Jin-bo
Zeng, Fang
Zhu, Yuan-qiang
Yu, Shu-guang
Yin, Hai-yan
Tang, Yong
Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi
title Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi
title_full Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi
title_fullStr Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi
title_full_unstemmed Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi
title_short Local Anesthesia at ST36 to Reveal Responding Brain Areas to deqi
title_sort local anesthesia at st36 to reveal responding brain areas to deqi
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914330/
https://www.ncbi.nlm.nih.gov/pubmed/24550995
http://dx.doi.org/10.1155/2014/987365
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