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Genetic Complexity in a Drosophila Model of Diabetes-Associated Misfolded Human Proinsulin

Drosophila melanogaster has been widely used as a model of human Mendelian disease, but its value in modeling complex disease has received little attention. Fly models of complex disease would enable high-resolution mapping of disease-modifying loci and the identification of novel targets for therap...

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Detalles Bibliográficos
Autores principales:	Park, Soo-Young, Ludwig, Michael Z., Tamarina, Natalia A., He, Bin Z., Carl, Sarah H., Dickerson, Desiree A., Barse, Levi, Arun, Bharath, Williams, Calvin L., Miles, Cecelia M., Philipson, Louis H., Steiner, Donald F., Bell, Graeme I., Kreitman, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2014
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914625/ https://www.ncbi.nlm.nih.gov/pubmed/24281154 http://dx.doi.org/10.1534/genetics.113.157602

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