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Combination of SLC administration and Tregs depletion is an attractive strategy for targeting hepatocellular carcinoma

BACKGROUND: Secondary lymphoid tissue chemokine (SLC) is a key CC chemokine for chemotaxis of immune cells and has been an attractive candidate for anti-tumor treatments. However, among the immune cells recruited by SLC to tumors, the CD25(+) Foxp3(+) regulatory T cells (Tregs) compromise the anti-t...

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Detalles Bibliográficos
Autores principales: Chen, Long, Zhou, Shuang, Qin, Jie, Hu, Heng, Ma, Huiying, Liu, Binbin, Wang, Xuan, Ma, Jiaqi, Ye, Shenglong, Zhong, Cuiping, Zhou, Guomin, Liang, Chunmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914677/
https://www.ncbi.nlm.nih.gov/pubmed/24304581
http://dx.doi.org/10.1186/1476-4598-12-153