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Real-Time, Transcranial Monitoring of Safe Blood-Brain Barrier Opening in Non-Human Primates
The delivery of drugs to specific neural targets faces two fundamental problems: (1) most drugs do not cross the blood-brain barrier, and (2) those that do, spread to the entire brain. To date, there exists only one non-invasive methodology with the potential to solve these problems: selective blood...
Autores principales: | Marquet, Fabrice, Teichert, Tobias, Wu, Shih-Ying, Tung, Yao-Sheng, Downs, Matthew, Wang, Shutao, Chen, Cherry, Ferrera, Vincent, Konofagou, Elisa E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914779/ https://www.ncbi.nlm.nih.gov/pubmed/24505248 http://dx.doi.org/10.1371/journal.pone.0084310 |
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