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Transmembrane Collagen XVII Modulates Integrin Dependent Keratinocyte Migration via PI3K/Rac1 Signaling

The hemidesmosomal transmembrane component collagen XVII (ColXVII) plays an important role in the anchorage of the epidermis to the underlying basement membrane. However, this adhesion protein seems to be also involved in the regulation of keratinocyte migration, since its expression in these cells...

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Detalles Bibliográficos
Autores principales: Löffek, Stefanie, Hurskainen, Tiina, Jackow, Joanna, Sigloch, Florian Christoph, Schilling, Oliver, Tasanen, Kaisa, Bruckner-Tuderman, Leena, Franzke, Claus-Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914815/
https://www.ncbi.nlm.nih.gov/pubmed/24505282
http://dx.doi.org/10.1371/journal.pone.0087263