Cargando…

Steroid Resistance in COPD? Overlap and Differential Anti-Inflammatory Effects in Smokers and Ex-Smokers

BACKGROUND: Inhaled corticosteroids (ICS) reduce exacerbation rates and improve health status but can increase the risk of pneumonia in COPD. The GLUCOLD study, investigating patients with mild-to-moderate COPD, has shown that long-term (2.5-year) ICS therapy induces anti-inflammatory effects. The l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hoonhorst, Susan J. M., ten Hacken, Nick H. T., Vonk, Judith M., Timens, Wim, Hiemstra, Pieter S., Lapperre, Thérèse S., Sterk, Peter J., Postma, Dirkje S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914834/ https://www.ncbi.nlm.nih.gov/pubmed/24505290 http://dx.doi.org/10.1371/journal.pone.0087443

Ejemplares similares

Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial
por: Snoeck-Stroband, Jiska B., et al.
Publicado: (2015)

Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial
por: Kunz, Lisette I. Z., et al.
Publicado: (2013)

Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers
por: Willemse, Brigitte WM, et al.
Publicado: (2005)

Acute effects of cigarette smoking on inflammation in healthy intermittent smokers
por: van der Vaart, Hester, et al.
Publicado: (2005)

Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease
por: Budulac, Simona E., et al.
Publicado: (2012)

Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study
por: Fattahi, Fatemeh, et al.
Publicado: (2013)

Smoking cessation and bronchial epithelial remodelling in COPD: a cross-sectional study
por: Lapperre, Thérèse S, et al.
Publicado: (2007)

Predictors of clinical response to extrafine and non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma
por: Gafar, Fajri, et al.
Publicado: (2018)

Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD
por: Kunz, Lisette IZ, et al.
Publicado: (2011)

Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD
por: Hoonhorst, Susan JM, et al.
Publicado: (2014)

Reticular basement membrane in asthma and COPD: Similar thickness, yet different composition
por: Liesker, Jeroen JW, et al.
Publicado: (2009)

Low-dose CT measurements of airway dimensions and emphysema associated with airflow limitation in heavy smokers: a cross sectional study
por: Dijkstra, Akkelies E, et al.
Publicado: (2013)

Predictors of COPD in symptomatic smokers and ex-smokers seen in primary care
por: Tupper, Oliver Djurhuus, et al.
Publicado: (2018)

High miR203a-3p and miR-375 expression in the airways of smokers with and without COPD
por: van Nijnatten, Jos, et al.
Publicado: (2022)

Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD
por: Babusyte, Agne, et al.
Publicado: (2007)

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers
por: Faiz, Alen, et al.
Publicado: (2019)

Increased levels of (class switched) memory B cells in peripheral blood of current smokers
por: Brandsma, Corry-Anke, et al.
Publicado: (2009)

Nicotinic Acetylcholine Receptor Variants Are Related to Smoking Habits, but Not Directly to COPD
por: Budulac, Simona E., et al.
Publicado: (2012)

Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD
por: Budulac, Simona E, et al.
Publicado: (2010)

Association of mast cells with lung function in chronic obstructive pulmonary disease
por: Gosman, Margot ME, et al.
Publicado: (2008)

Tumor necrosis factor receptor 2 as a possible marker of COPD in smokers and ex-smokers
por: Caram, Laura Miranda de Oliveira, et al.
Publicado: (2017)

Different Characteristics of Ex-Smokers and Current Smokers with COPD: A Cross-Sectional Study in China
por: Liu, Cong, et al.
Publicado: (2020)

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression
por: Boudewijn, Ilse M., et al.
Publicado: (2017)

No association between DNA methylation and COPD in never and current smokers
por: de Vries, Maaike, et al.
Publicado: (2018)

Status of thiocyanate levels in the serum and saliva of non-smokers, ex-smokers and smokers
por: Madiyal, Ananya, et al.
Publicado: (2018)

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity
por: van den Berge, Maarten, et al.
Publicado: (2014)

Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking
por: Franciosi, Lorenza, et al.
Publicado: (2014)

Advanced glycation endproducts and their receptor in different body compartments in COPD
por: Hoonhorst, Susan J. M., et al.
Publicado: (2016)

Prevalence of NRT Use and Associated Nicotine Intake in Smokers, Recent Ex-Smokers and Longer-Term Ex-Smokers
por: Shahab, Lion, et al.
Publicado: (2014)

Opportunistic screening for COPD in primary care: a pooled analysis of 6,710 symptomatic smokers and ex-smokers
por: Katsimigas, Andreas, et al.
Publicado: (2019)

Early Detection of COPD: An Opportunistic Case Finding Study in Smokers and Ex-Smokers Visiting a Medical Centre
por: Rokach, Ariel, et al.
Publicado: (2021)

Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma
por: Ierodiakonou, Despo, et al.
Publicado: (2016)

Cost-effectiveness of screening smokers and ex-smokers for lung cancer in the Netherlands in different age groups
por: Al Khayat, Mohamed N. M. T., et al.
Publicado: (2022)

Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study
por: Lo Tam Loi, Adèle T, et al.
Publicado: (2013)

Lower Corticosteroid Skin Blanching Response Is Associated with Severe COPD
por: Hoonhorst, Susan J. M., et al.
Publicado: (2014)

Old dilemma: asthma with irreversible airway obstruction or COPD
por: Fattahi, Fatemeh, et al.
Publicado: (2015)

GST-omega genes interact with environmental tobacco smoke on adult level of lung function
por: de Jong, Kim, et al.
Publicado: (2013)

Rate of progression of CT-quantified emphysema in male current and ex-smokers: a follow-up study
por: Mohamed Hoesein, Firdaus AA, et al.
Publicado: (2013)

Assessment of Tobacco-Related Approach and Attentional Biases in Smokers, Cravers, Ex-Smokers, and Non-Smokers
por: Woud, Marcella L., et al.
Publicado: (2016)

Prevalence and incidence of COPD in smokers and non-smokers: the Rotterdam Study
por: Terzikhan, Natalie, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3prfrlegj7v5gh276t8tdng7ce