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Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ(10), and angiotensin receptor blocker, losartan, on cardiovascular function

OBJECTIVE: Mitochondria-derived reactive oxygen species (ROS) play important roles in the development of cardiovascular disease highlighting the need for novel targeted therapies. This study assessed the potential therapeutic benefit of combining the mitochondria-specific antioxidant, MitoQ(10), wit...

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Detalles Bibliográficos
Autores principales: McLachlan, Jennifer, Beattie, Elisabeth, Murphy, Michael P., Koh-Tan, Caline H.H., Olson, Erin, Beattie, Wendy, Dominiczak, Anna F., Nicklin, Stuart A., Graham, Delyth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914904/
https://www.ncbi.nlm.nih.gov/pubmed/24309493
http://dx.doi.org/10.1097/HJH.0000000000000054