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A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle

The expression of N-glycolylneuraminic acid (Neu5Gc) and the cytotoxic T cell (CT) carbohydrate can impact the severity of muscular dystrophy arising from the loss of dystrophin in mdx mice. Here, we describe the expression of these two glycans in skeletal muscles of dogs and humans with or without...

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Detalles Bibliográficos
Autores principales: Martin, Paul T., Golden, Bethannie, Okerblom, Jonathan, Camboni, Marybeth, Chandrasekharan, Kumaran, Xu, Rui, Varki, Ajit, Flanigan, Kevin M., Kornegay, Joe N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914967/
https://www.ncbi.nlm.nih.gov/pubmed/24505439
http://dx.doi.org/10.1371/journal.pone.0088226

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