Pristane-Induced Arthritis Loci Interact with the Slc11a1 Gene to Determine Susceptibility in Mice Selected for High Inflammation

AIRmax (maximal inflammation) and AIRmin (minimal inflammation) mice show distinct susceptibilities to pristane-induced arthritis (PIA). The Slc11a1 gene, which regulates macrophage and neutrophil activity, is involved in this infirmity. AIRmax(SS) mice homozygous for the non-functional Slc11a1 S (g...

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Detalles Bibliográficos
Autores principales: De Franco, Marcelo, Peters, Luciana C., Correa, Mara A., Galvan, Antonella, Canhamero, Tatiane, Borrego, Andrea, Jensen, José R., Gonçalves, Jussara, Cabrera, Wafa H. K., Starobinas, Nancy, Ribeiro, Orlando G., Dragani, Tommaso, Ibañez, Olga M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914970/
https://www.ncbi.nlm.nih.gov/pubmed/24505471
http://dx.doi.org/10.1371/journal.pone.0088302

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