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Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands

We have previously discovered a synergistically therapeutic combination of two Toll-like receptor ligands, an oligodeoxynucleotide (ODN) and Pam2CSK4. Aerosolization of these ligands stimulates innate immunity within the lungs to prevent pneumonia from bacterial and viral pathogens. Here we examined...

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Detalles Bibliográficos
Autores principales:	Alfaro, Victoria Y., Goldblatt, David L., Valverde, Gabriella R., Munsell, Mark F., Quinton, Lee J., Walker, Adam K., Dantzer, Robert, Varadhachary, Atul, Scott, Brenton L., Evans, Scott E., Tuvim, Michael J., Dickey, Burton F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915096/ https://www.ncbi.nlm.nih.gov/pubmed/24567720 http://dx.doi.org/10.3389/fphar.2014.00008

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