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Current view on the functional regulation of the neuronal K(+)-Cl(−) cotransporter KCC2

In the mammalian central nervous system (CNS), the inhibitory strength of chloride (Cl(−))-permeable GABA(A) and glycine receptors (GABA(A)R and GlyR) depends on the intracellular Cl(−) concentration ([Cl(−)](i)). Lowering [Cl(−)](i) enhances inhibition, whereas raising [Cl(−)](i) facilitates neuron...

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Detalles Bibliográficos
Autores principales:	Medina, Igor, Friedel, Perrine, Rivera, Claudio, Kahle, Kristopher T., Kourdougli, Nazim, Uvarov, Pavel, Pellegrino, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915100/ https://www.ncbi.nlm.nih.gov/pubmed/24567703 http://dx.doi.org/10.3389/fncel.2014.00027

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