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Cytoplasmic 5′-3′ exonuclease Xrn1p is also a genome-wide transcription factor in yeast

The 5′ to 3′ exoribonuclease Xrn1 is a large protein involved in cytoplasmatic mRNA degradation as a critical component of the major decaysome. Its deletion in the yeast Saccharomyces cerevisiae is not lethal, but it has multiple physiological effects. In a previous study, our group showed that dele...

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Detalles Bibliográficos
Autores principales: Medina, Daniel A., Jordán-Pla, Antonio, Millán-Zambrano, Gonzalo, Chávez, Sebastián, Choder, Mordechai, Pérez-Ortín, José E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915102/
https://www.ncbi.nlm.nih.gov/pubmed/24567736
http://dx.doi.org/10.3389/fgene.2014.00001