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Breast cancer survival and prognosis by screening history
BACKGROUND: Cancers not detected by breast screening are commonly assumed to have poorer prognosis. METHODS: We examined the survival experience of all women aged 50–74 years diagnosed with a first breast cancer between 1998 and 2006 in British Columbia, Canada and determined their screening experie...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915113/ https://www.ncbi.nlm.nih.gov/pubmed/24300976 http://dx.doi.org/10.1038/bjc.2013.732 |
Sumario: | BACKGROUND: Cancers not detected by breast screening are commonly assumed to have poorer prognosis. METHODS: We examined the survival experience of all women aged 50–74 years diagnosed with a first breast cancer between 1998 and 2006 in British Columbia, Canada and determined their screening experience. Disease-specific survival rates were calculated and, for cases diagnosed in 2002, prognostic factors (size, nodal involvement, grade ER status and stage) were examined by time since screening. RESULTS: Breast cancers diagnosed at screening had the best survival (P<0.001). Cancers detected within 12 months of a negative screen had similar survival rates (P=0.98) to those diagnosed within 12–23 and 24–47 months, with other non-screen-detected cancers having poorer survival (P<0.001). The prognostic profile of cancers diagnosed in 2002 followed a similar pattern. INTERPRETATION: There was no evidence that cancers diagnosed within 12 months had poorer prognosis than those diagnosed up to 48 months following screening. |
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