Cargando…
Breast cancer survival and prognosis by screening history
BACKGROUND: Cancers not detected by breast screening are commonly assumed to have poorer prognosis. METHODS: We examined the survival experience of all women aged 50–74 years diagnosed with a first breast cancer between 1998 and 2006 in British Columbia, Canada and determined their screening experie...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915113/ https://www.ncbi.nlm.nih.gov/pubmed/24300976 http://dx.doi.org/10.1038/bjc.2013.732 |
_version_ | 1782302527610421248 |
---|---|
author | Coldman, A J Phillips, N |
author_facet | Coldman, A J Phillips, N |
author_sort | Coldman, A J |
collection | PubMed |
description | BACKGROUND: Cancers not detected by breast screening are commonly assumed to have poorer prognosis. METHODS: We examined the survival experience of all women aged 50–74 years diagnosed with a first breast cancer between 1998 and 2006 in British Columbia, Canada and determined their screening experience. Disease-specific survival rates were calculated and, for cases diagnosed in 2002, prognostic factors (size, nodal involvement, grade ER status and stage) were examined by time since screening. RESULTS: Breast cancers diagnosed at screening had the best survival (P<0.001). Cancers detected within 12 months of a negative screen had similar survival rates (P=0.98) to those diagnosed within 12–23 and 24–47 months, with other non-screen-detected cancers having poorer survival (P<0.001). The prognostic profile of cancers diagnosed in 2002 followed a similar pattern. INTERPRETATION: There was no evidence that cancers diagnosed within 12 months had poorer prognosis than those diagnosed up to 48 months following screening. |
format | Online Article Text |
id | pubmed-3915113 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-39151132015-02-04 Breast cancer survival and prognosis by screening history Coldman, A J Phillips, N Br J Cancer Short Communication BACKGROUND: Cancers not detected by breast screening are commonly assumed to have poorer prognosis. METHODS: We examined the survival experience of all women aged 50–74 years diagnosed with a first breast cancer between 1998 and 2006 in British Columbia, Canada and determined their screening experience. Disease-specific survival rates were calculated and, for cases diagnosed in 2002, prognostic factors (size, nodal involvement, grade ER status and stage) were examined by time since screening. RESULTS: Breast cancers diagnosed at screening had the best survival (P<0.001). Cancers detected within 12 months of a negative screen had similar survival rates (P=0.98) to those diagnosed within 12–23 and 24–47 months, with other non-screen-detected cancers having poorer survival (P<0.001). The prognostic profile of cancers diagnosed in 2002 followed a similar pattern. INTERPRETATION: There was no evidence that cancers diagnosed within 12 months had poorer prognosis than those diagnosed up to 48 months following screening. Nature Publishing Group 2014-02-04 2013-12-03 /pmc/articles/PMC3915113/ /pubmed/24300976 http://dx.doi.org/10.1038/bjc.2013.732 Text en Copyright © 2014 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/3.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
spellingShingle | Short Communication Coldman, A J Phillips, N Breast cancer survival and prognosis by screening history |
title | Breast cancer survival and prognosis by screening history |
title_full | Breast cancer survival and prognosis by screening history |
title_fullStr | Breast cancer survival and prognosis by screening history |
title_full_unstemmed | Breast cancer survival and prognosis by screening history |
title_short | Breast cancer survival and prognosis by screening history |
title_sort | breast cancer survival and prognosis by screening history |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915113/ https://www.ncbi.nlm.nih.gov/pubmed/24300976 http://dx.doi.org/10.1038/bjc.2013.732 |
work_keys_str_mv | AT coldmanaj breastcancersurvivalandprognosisbyscreeninghistory AT phillipsn breastcancersurvivalandprognosisbyscreeninghistory |