Statin use is not associated with reduced risk of skin cancer: a meta-analysis

BACKGROUND: There is contradictory evidence about the association between statin and skin cancer. METHODS: Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated. RESULT: A total of 21 arti...

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Detalles Bibliográficos
Autores principales: Li, X, Wu, X B, Chen, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915126/
https://www.ncbi.nlm.nih.gov/pubmed/24366301
http://dx.doi.org/10.1038/bjc.2013.762
Descripción
Sumario:BACKGROUND: There is contradictory evidence about the association between statin and skin cancer. METHODS: Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated. RESULT: A total of 21 articles with 29 studies were identified. No association was found between statin and skin cancer among neither melanoma (RR, 0.94; 95% CI, 0.85–1.04) nor non-melanoma skin cancer (RR, 1.03; 95% CI, 0.90–1.19). CONCLUSION: Our meta-analysis does not support a potential role of statin use in the prevention of skin cancer.

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