Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling

BACKGROUND: Cancer-associated fibroblasts (CAFs) activated by tumour cells are the predominant type of stromal cells in breast cancer tissue. The reciprocal effect of CAFs on breast cancer cells and the underlying molecular mechanisms are not fully characterised. METHODS: Stromal fibroblasts were is...

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Detalles Bibliográficos
Autores principales: Yu, Y, Xiao, C-H, Tan, L-D, Wang, Q-S, Li, X-Q, Feng, Y-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915130/
https://www.ncbi.nlm.nih.gov/pubmed/24335925
http://dx.doi.org/10.1038/bjc.2013.768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915130/
https://www.ncbi.nlm.nih.gov/pubmed/24335925
http://dx.doi.org/10.1038/bjc.2013.768

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