Cargando…

Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd

BACKGROUND: Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Es...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayatollahi, J, Shahcheraghi, S H, Akhondi, R, Soluti, SS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Sadoughi University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915452/
https://www.ncbi.nlm.nih.gov/pubmed/24575275
_version_ 1782302586280345600
author Ayatollahi, J
Shahcheraghi, S H
Akhondi, R
Soluti, SS
author_facet Ayatollahi, J
Shahcheraghi, S H
Akhondi, R
Soluti, SS
author_sort Ayatollahi, J
collection PubMed
description BACKGROUND: Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Escherichia coli isolated from children in Shahid Sadoughi hospital of Yazd. MATERIALS AND METHODS: In this cross-sectional study, antimicrobial susceptibility to cefixime , cefotaxime , ceftazidime , ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid was determined for 148 E. coli isolates obtained from patients less than 18 years of age (hospitalized and outpatient) in Shahid Sadoughi hospital of Yazd. RESULTS: Ciprofloxacin was the most active antibacterial agent (78% susceptible), followed by gentamicin. High rates of resistance were observed for cefixime (57.9%) and cotrimoxazole. The results for ceftriaxone, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid were insignificant with P-value= 0.302, P-value= 0.550, P-value= 0.334, P-value= 0.084, P-value= 0.948, P-value= 0.686, P-value= 0.120 and P-value= 0.162, respectively. The results were significant for cefixime with P-value= 0.013. CONCLUSION: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents. It also helps to limit E. coli spread.
format Online
Article
Text
id pubmed-3915452
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Shahid Sadoughi University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-39154522014-02-26 Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd Ayatollahi, J Shahcheraghi, S H Akhondi, R Soluti, SS Iran J Ped Hematol Oncol Original Article BACKGROUND: Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Escherichia coli isolated from children in Shahid Sadoughi hospital of Yazd. MATERIALS AND METHODS: In this cross-sectional study, antimicrobial susceptibility to cefixime , cefotaxime , ceftazidime , ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid was determined for 148 E. coli isolates obtained from patients less than 18 years of age (hospitalized and outpatient) in Shahid Sadoughi hospital of Yazd. RESULTS: Ciprofloxacin was the most active antibacterial agent (78% susceptible), followed by gentamicin. High rates of resistance were observed for cefixime (57.9%) and cotrimoxazole. The results for ceftriaxone, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid were insignificant with P-value= 0.302, P-value= 0.550, P-value= 0.334, P-value= 0.084, P-value= 0.948, P-value= 0.686, P-value= 0.120 and P-value= 0.162, respectively. The results were significant for cefixime with P-value= 0.013. CONCLUSION: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents. It also helps to limit E. coli spread. Shahid Sadoughi University of Medical Sciences 2013 2013-04-22 /pmc/articles/PMC3915452/ /pubmed/24575275 Text en © 2013: Iranian Journal of Pediatric Hematology Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ayatollahi, J
Shahcheraghi, S H
Akhondi, R
Soluti, SS
Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
title Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
title_full Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
title_fullStr Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
title_full_unstemmed Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
title_short Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
title_sort antibiotic resistance patterns of escherichia coli isolated from children in shahid sadoughi hospital of yazd
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915452/
https://www.ncbi.nlm.nih.gov/pubmed/24575275
work_keys_str_mv AT ayatollahij antibioticresistancepatternsofescherichiacoliisolatedfromchildreninshahidsadoughihospitalofyazd
AT shahcheraghish antibioticresistancepatternsofescherichiacoliisolatedfromchildreninshahidsadoughihospitalofyazd
AT akhondir antibioticresistancepatternsofescherichiacoliisolatedfromchildreninshahidsadoughihospitalofyazd
AT solutiss antibioticresistancepatternsofescherichiacoliisolatedfromchildreninshahidsadoughihospitalofyazd