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Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
BACKGROUND: Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Es...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shahid Sadoughi University of Medical Sciences
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915452/ https://www.ncbi.nlm.nih.gov/pubmed/24575275 |
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author | Ayatollahi, J Shahcheraghi, S H Akhondi, R Soluti, SS |
author_facet | Ayatollahi, J Shahcheraghi, S H Akhondi, R Soluti, SS |
author_sort | Ayatollahi, J |
collection | PubMed |
description | BACKGROUND: Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Escherichia coli isolated from children in Shahid Sadoughi hospital of Yazd. MATERIALS AND METHODS: In this cross-sectional study, antimicrobial susceptibility to cefixime , cefotaxime , ceftazidime , ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid was determined for 148 E. coli isolates obtained from patients less than 18 years of age (hospitalized and outpatient) in Shahid Sadoughi hospital of Yazd. RESULTS: Ciprofloxacin was the most active antibacterial agent (78% susceptible), followed by gentamicin. High rates of resistance were observed for cefixime (57.9%) and cotrimoxazole. The results for ceftriaxone, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid were insignificant with P-value= 0.302, P-value= 0.550, P-value= 0.334, P-value= 0.084, P-value= 0.948, P-value= 0.686, P-value= 0.120 and P-value= 0.162, respectively. The results were significant for cefixime with P-value= 0.013. CONCLUSION: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents. It also helps to limit E. coli spread. |
format | Online Article Text |
id | pubmed-3915452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Shahid Sadoughi University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-39154522014-02-26 Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd Ayatollahi, J Shahcheraghi, S H Akhondi, R Soluti, SS Iran J Ped Hematol Oncol Original Article BACKGROUND: Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Escherichia coli isolated from children in Shahid Sadoughi hospital of Yazd. MATERIALS AND METHODS: In this cross-sectional study, antimicrobial susceptibility to cefixime , cefotaxime , ceftazidime , ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid was determined for 148 E. coli isolates obtained from patients less than 18 years of age (hospitalized and outpatient) in Shahid Sadoughi hospital of Yazd. RESULTS: Ciprofloxacin was the most active antibacterial agent (78% susceptible), followed by gentamicin. High rates of resistance were observed for cefixime (57.9%) and cotrimoxazole. The results for ceftriaxone, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, imipenem, cotrimoxazole and nalidixic acid were insignificant with P-value= 0.302, P-value= 0.550, P-value= 0.334, P-value= 0.084, P-value= 0.948, P-value= 0.686, P-value= 0.120 and P-value= 0.162, respectively. The results were significant for cefixime with P-value= 0.013. CONCLUSION: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents. It also helps to limit E. coli spread. Shahid Sadoughi University of Medical Sciences 2013 2013-04-22 /pmc/articles/PMC3915452/ /pubmed/24575275 Text en © 2013: Iranian Journal of Pediatric Hematology Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ayatollahi, J Shahcheraghi, S H Akhondi, R Soluti, SS Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd |
title | Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd |
title_full | Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd |
title_fullStr | Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd |
title_full_unstemmed | Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd |
title_short | Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd |
title_sort | antibiotic resistance patterns of escherichia coli isolated from children in shahid sadoughi hospital of yazd |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915452/ https://www.ncbi.nlm.nih.gov/pubmed/24575275 |
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