Cargando…
Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
BACKGROUND: Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shahid Sadoughi University of Medical Sciences
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915453/ https://www.ncbi.nlm.nih.gov/pubmed/24575276 |
_version_ | 1782302586527809536 |
---|---|
author | Taghipour Zahir, Sh Miratashi, S A Nazemian, M Zand, S |
author_facet | Taghipour Zahir, Sh Miratashi, S A Nazemian, M Zand, S |
author_sort | Taghipour Zahir, Sh |
collection | PubMed |
description | BACKGROUND: Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without other organ involvement excision alone with close monitoring is a treatment of choiceand the prognosis is excellent. CASE PRESENTATION: A 12 year -old male with a nodular lesion involving the inner can thus of the right eye was admitted to ophthalmology clinic. The lesion was painless and the nodule size gradually increased over a period of 6 months.Excisional biopsy demonstrated follicular lymphoma composed of neoplastic lymphoid cells which arranged in follicular pattern without germinal centers. Neoplastic cells were positive for Bcl2 and CD20. CONCLUSION: Although follicular lymphoma of the conjunctiva is rare in childhood but it could be considered as one of the differential diagnosis in this age group. |
format | Online Article Text |
id | pubmed-3915453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Shahid Sadoughi University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-39154532014-02-26 Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male Taghipour Zahir, Sh Miratashi, S A Nazemian, M Zand, S Iran J Ped Hematol Oncol Case Report BACKGROUND: Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without other organ involvement excision alone with close monitoring is a treatment of choiceand the prognosis is excellent. CASE PRESENTATION: A 12 year -old male with a nodular lesion involving the inner can thus of the right eye was admitted to ophthalmology clinic. The lesion was painless and the nodule size gradually increased over a period of 6 months.Excisional biopsy demonstrated follicular lymphoma composed of neoplastic lymphoid cells which arranged in follicular pattern without germinal centers. Neoplastic cells were positive for Bcl2 and CD20. CONCLUSION: Although follicular lymphoma of the conjunctiva is rare in childhood but it could be considered as one of the differential diagnosis in this age group. Shahid Sadoughi University of Medical Sciences 2013 2013-04-22 /pmc/articles/PMC3915453/ /pubmed/24575276 Text en © 2013: Iranian Journal of Pediatric Hematology Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Taghipour Zahir, Sh Miratashi, S A Nazemian, M Zand, S Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male |
title | Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male |
title_full | Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male |
title_fullStr | Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male |
title_full_unstemmed | Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male |
title_short | Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male |
title_sort | primary follicular lymphoma of the conjunctiva in a 12 year-old male |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915453/ https://www.ncbi.nlm.nih.gov/pubmed/24575276 |
work_keys_str_mv | AT taghipourzahirsh primaryfollicularlymphomaoftheconjunctivaina12yearoldmale AT miratashisa primaryfollicularlymphomaoftheconjunctivaina12yearoldmale AT nazemianm primaryfollicularlymphomaoftheconjunctivaina12yearoldmale AT zands primaryfollicularlymphomaoftheconjunctivaina12yearoldmale |