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Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male

BACKGROUND: Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without...

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Autores principales: Taghipour Zahir, Sh, Miratashi, S A, Nazemian, M, Zand, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Sadoughi University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915453/
https://www.ncbi.nlm.nih.gov/pubmed/24575276
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author Taghipour Zahir, Sh
Miratashi, S A
Nazemian, M
Zand, S
author_facet Taghipour Zahir, Sh
Miratashi, S A
Nazemian, M
Zand, S
author_sort Taghipour Zahir, Sh
collection PubMed
description BACKGROUND: Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without other organ involvement excision alone with close monitoring is a treatment of choiceand the prognosis is excellent. CASE PRESENTATION: A 12 year -old male with a nodular lesion involving the inner can thus of the right eye was admitted to ophthalmology clinic. The lesion was painless and the nodule size gradually increased over a period of 6 months.Excisional biopsy demonstrated follicular lymphoma composed of neoplastic lymphoid cells which arranged in follicular pattern without germinal centers. Neoplastic cells were positive for Bcl2 and CD20. CONCLUSION: Although follicular lymphoma of the conjunctiva is rare in childhood but it could be considered as one of the differential diagnosis in this age group.
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spelling pubmed-39154532014-02-26 Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male Taghipour Zahir, Sh Miratashi, S A Nazemian, M Zand, S Iran J Ped Hematol Oncol Case Report BACKGROUND: Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without other organ involvement excision alone with close monitoring is a treatment of choiceand the prognosis is excellent. CASE PRESENTATION: A 12 year -old male with a nodular lesion involving the inner can thus of the right eye was admitted to ophthalmology clinic. The lesion was painless and the nodule size gradually increased over a period of 6 months.Excisional biopsy demonstrated follicular lymphoma composed of neoplastic lymphoid cells which arranged in follicular pattern without germinal centers. Neoplastic cells were positive for Bcl2 and CD20. CONCLUSION: Although follicular lymphoma of the conjunctiva is rare in childhood but it could be considered as one of the differential diagnosis in this age group. Shahid Sadoughi University of Medical Sciences 2013 2013-04-22 /pmc/articles/PMC3915453/ /pubmed/24575276 Text en © 2013: Iranian Journal of Pediatric Hematology Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Taghipour Zahir, Sh
Miratashi, S A
Nazemian, M
Zand, S
Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
title Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
title_full Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
title_fullStr Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
title_full_unstemmed Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
title_short Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
title_sort primary follicular lymphoma of the conjunctiva in a 12 year-old male
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915453/
https://www.ncbi.nlm.nih.gov/pubmed/24575276
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