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Therapeutic Evaluation of Epstein-Barr Virus-encoded Latent Membrane Protein-1 Targeted DNAzyme for Treating of Nasopharyngeal Carcinomas

The ability of the 10–23 DNAzyme to specifically cleave RNA with high efficiency has fuelled expectation that this agent may have useful applications for targeted therapy. Here, we, for the first time, investigated the antitumor and radiosensitizing effects of a DNAzyme (DZ1) targeted to the Epstein...

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Detalles Bibliográficos
Autores principales: Cao, Ya, Yang, Lifang, Jiang, Wuzhong, Wang, Xiaoyi, Liao, Weihua, Tan, Guolin, Liao, Yuping, Qiu, Yuanzheng, Feng, Deyun, Tang, Faqing, Hou, Bob L, Zhang, Ling, Fu, Jia, He, Fengjiao, Liu, Xiaoyu, Jiang, Wenjuan, Yang, Tubao, Sun, Lun-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916047/
https://www.ncbi.nlm.nih.gov/pubmed/24322331
http://dx.doi.org/10.1038/mt.2013.257