Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser(1177)/Thr(497) of endothelial nitric oxide synthase in diabetic mice

BACKGROUND: Azilsartan, an angiotensin II type 1 (AT1) receptor blocker (ARB), has a higher affinity for and slower dissociation from AT1 receptors and shows stronger inverse agonism compared to other ARBs. Possible benefits of azilsartan in diabetic vascular dysfunction have not been established. M...

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Detalles Bibliográficos
Autores principales: Matsumoto, Sachiko, Shimabukuro, Michio, Fukuda, Daiju, Soeki, Takeshi, Yamakawa, Ken, Masuzaki, Hiroaki, Sata, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916073/
https://www.ncbi.nlm.nih.gov/pubmed/24485356
http://dx.doi.org/10.1186/1475-2840-13-30

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