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T lymphocytes export proteasomes by way of microparticles: a possible mechanism for generation of extracellular proteasomes
The 20S proteasome is almost exclusively localized within cells. High levels of extracellular proteasomes are also found circulating in the blood plasma of patients suffering from a variety of inflammatory, autoimmune and neoplastic diseases. However, the origin of these proteasomes remained enigmat...
Autores principales: | Bochmann, Isabel, Ebstein, Frédéric, Lehmann, Andrea, Wohlschlaeger, Jeremias, Sixt, Stephan Urs, Kloetzel, Peter-Michael, Dahlmann, Burkhardt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916118/ https://www.ncbi.nlm.nih.gov/pubmed/24304442 http://dx.doi.org/10.1111/jcmm.12160 |
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