Cargando…

Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma

High-risk human papillomavirus (HPV)-positive head and neck squamous cell carcinomas (HNSCCs) are highly invasive; however the identity of downstream effectors responsible for their aggressive phenotype remains underinvestigated. Here, we report that HPV-mediated up-regulation of heparanase enzyme c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirshoren, Nir, Bulvik, Raanan, Neuman, Tzahi, Rubinstein, Ariel M, Meirovitz, Amichay, Elkin, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916129/ https://www.ncbi.nlm.nih.gov/pubmed/24286246 http://dx.doi.org/10.1111/jcmm.12179

Ejemplares similares

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
por: Gil, Natali, et al.
Publicado: (2012)

Radiation-Induced Nephropathy in the Murine Model Is Ameliorated by Targeting Heparanase
por: Abecassis, Alexia, et al.
Publicado: (2023)

Regulation of Heparanase in Diabetes-Associated Pancreatic Carcinoma
por: Goldberg, Rachel, et al.
Publicado: (2019)

Modified bi‐weekly cetuximab‐cisplatin and 5‐FU/leucovorin based regimen for effective treatment of recurrent/metastatic head and neck squamous cell carcinoma to reduce chemotherapy exposure of patients
por: Meirovitz, Amichay, et al.
Publicado: (2021)

Heparanase augments insulin receptor signaling in breast carcinoma
por: Goldberg, Rachel, et al.
Publicado: (2016)

Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model
por: Gallimidi, Adi Binder, et al.
Publicado: (2015)

Trimodal therapy in T2‐4aN0M0 bladder cancer––How to select the best candidate?
por: Gofrit, Ofer N., et al.
Publicado: (2020)

Radiosensitization approaches for HPV‐positive and HPV‐negative head and neck squamous carcinomas
por: Dok, Rüveyda, et al.
Publicado: (2019)

The radiobiology of HPV-positive and HPV-negative head and neck squamous cell carcinoma
por: Zhou, Chumin, et al.
Publicado: (2020)

Sentinel Lymph Node Identification in Cutaneous Head & Neck Cancer ‐ Lymphoscintigraphy Late Phase
por: Hirshoren, Nir, et al.
Publicado: (2022)

Radioimmunotherapy in HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Zhou, Xin, et al.
Publicado: (2022)

Training and competence perception differences in otolaryngology and head and neck surgery training program – an anonymous electronic national survey
por: Hirshoren, Nir, et al.
Publicado: (2023)

Macrophages Upregulate Estrogen Receptor Expression in the Model of Obesity-Associated Breast Carcinoma
por: Nahmias Blank, Daniela, et al.
Publicado: (2022)

Advancements in the Management of HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Zeitlin, Ross, et al.
Publicado: (2015)

HPV Detection in Head and Neck Squamous Cell Carcinomas: What Is the Issue?
por: Augustin, Jeremy Gbenakpon, et al.
Publicado: (2020)

Analysis of the anatomical distribution of HPV genotypes in head and neck squamous papillomas
por: Hu, Huiying, et al.
Publicado: (2023)

Checkpoint inhibitors: Better outcomes among advanced cutaneous head and neck melanoma patients
por: Hirshoren, Nir, et al.
Publicado: (2020)

Cytokines levels, Severity of acute mucositis and the need of PEG tube installation during chemo-radiation for head and neck cancer - a prospective pilot study
por: Meirovitz, Amichay, et al.
Publicado: (2010)

Adaptive immune resistance in HPV-associated head and neck squamous cell carcinoma
por: Pai, Sara I.
Publicado: (2013)

Management of HPV-Related Squamous Cell Carcinoma of the Head and Neck: Pitfalls and Caveat
por: Perri, Francesco, et al.
Publicado: (2020)

An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
por: Carper, Miranda B., et al.
Publicado: (2019)

PYHIN Proteins and HPV: Role in the Pathogenesis of Head and Neck Squamous Cell Carcinoma
por: Riva, Giuseppe, et al.
Publicado: (2019)

Therapeutic strategies of different HPV status in Head and Neck Squamous Cell Carcinoma
por: Sun, Yingming, et al.
Publicado: (2021)

Characteristics of B lymphocyte infiltration in HPV(+) head and neck squamous cell carcinoma
por: Zhang, Siwei, et al.
Publicado: (2021)

De-Escalating Strategies in HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Economopoulou, Panagiota, et al.
Publicado: (2021)

Mechanisms of Cisplatin Resistance in HPV Negative Head and Neck Squamous Cell Carcinomas
por: Griso, Ana Belén, et al.
Publicado: (2022)

Proteome and phosphoproteome signatures of recurrence for HPV(+) head and neck squamous cell carcinoma
por: Kaneko, Tomonori, et al.
Publicado: (2022)

Comprehensive analysis of mitophagy in HPV-related head and neck squamous cell carcinoma
por: Yanan, Li, et al.
Publicado: (2023)

CT120A Acts as an Oncogene in Head and Neck Squamous Cell Carcinoma
por: Baltaci, Elif, et al.
Publicado: (2015)

HOXB7 acts as an oncogenic biomarker in head and neck squamous cell carcinoma
por: Wu, Xiang, et al.
Publicado: (2021)

Heparanase: a potential marker of worse prognosis in estrogen receptor-positive breast cancer
por: Zahavi, Tamar, et al.
Publicado: (2021)

In vitro effects of gamma-secretase inhibition in HPV-positive and HPV-negative head and neck squamous cell carcinoma
por: Varatanovic, Sara, et al.
Publicado: (2023)

Association of an intact E2 gene with higher HPV viral load, higher viral oncogene expression, and improved clinical outcome in HPV16 positive head and neck squamous cell carcinoma
por: Anayannis, Nicole V., et al.
Publicado: (2018)

Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma
por: Lechner, Matthias, et al.
Publicado: (2013)

Oncolytic activity of reovirus in HPV positive and negative head and neck squamous cell carcinoma
por: Cooper, Timothy, et al.
Publicado: (2015)

HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma
por: Fleming, Jason C., et al.
Publicado: (2019)

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas
por: Degli Esposti, Davide, et al.
Publicado: (2017)

HPV Involvement in the Tumor Microenvironment and Immune Treatment in Head and Neck Squamous Cell Carcinomas
por: Lechien, Jérôme R., et al.
Publicado: (2020)

Active HPV infection and its influence on survival in head and neck squamous-cell cancer
por: Janecka-Widła, Anna, et al.
Publicado: (2020)

A HPV16-related prognostic indicator for head and neck squamous cell carcinoma
por: Zhang, Qian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_33f167u8493jk3coqh9lpjcdud