Cargando…

Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature

Minimal deviation adenocarcinoma (MDA) of the uterine cervix, otherwise known as adenoma malignum, is a rare variant of cervical adenocarcinoma, which represents a diagnostic challenge in the field of gynecologic oncology, due to its benign-resembling histological characteristics. To achieve a bette...

Descripción completa

Detalles Bibliográficos
Autores principales: GUO, FEIFEI, HU, YALI, XU, XIAOFENG, LI, RONG, RU, TONG, WANG, JINGMEI, ZHOU, HUAIJUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916131/
https://www.ncbi.nlm.nih.gov/pubmed/24649256
http://dx.doi.org/10.3892/mco.2013.144
_version_ 1782302671971024896
author GUO, FEIFEI
HU, YALI
XU, XIAOFENG
LI, RONG
RU, TONG
WANG, JINGMEI
ZHOU, HUAIJUN
author_facet GUO, FEIFEI
HU, YALI
XU, XIAOFENG
LI, RONG
RU, TONG
WANG, JINGMEI
ZHOU, HUAIJUN
author_sort GUO, FEIFEI
collection PubMed
description Minimal deviation adenocarcinoma (MDA) of the uterine cervix, otherwise known as adenoma malignum, is a rare variant of cervical adenocarcinoma, which represents a diagnostic challenge in the field of gynecologic oncology, due to its benign-resembling histological characteristics. To achieve a better understanding of this disease, we present two cases of MDA: one case presented with profuse watery discharge and cervical enlargement, accompanied by retention cysts and hardening; the other presented with a history of myoma cervicis uteri. Both patients underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and pelvic lymphadenectomy and our follow-up indicated that the patients were still free of any disease. Subsequently, a literature review was performed and the results demonstrated that early diagnosis, clinical stage and surgical protocols are the main factors affecting the prognosis of MDA. Close follow-up of the cases may provide more information regarding this disease and the efficacy of the available therapeutic methods.
format Online
Article
Text
id pubmed-3916131
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-39161312014-03-19 Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature GUO, FEIFEI HU, YALI XU, XIAOFENG LI, RONG RU, TONG WANG, JINGMEI ZHOU, HUAIJUN Mol Clin Oncol Articles Minimal deviation adenocarcinoma (MDA) of the uterine cervix, otherwise known as adenoma malignum, is a rare variant of cervical adenocarcinoma, which represents a diagnostic challenge in the field of gynecologic oncology, due to its benign-resembling histological characteristics. To achieve a better understanding of this disease, we present two cases of MDA: one case presented with profuse watery discharge and cervical enlargement, accompanied by retention cysts and hardening; the other presented with a history of myoma cervicis uteri. Both patients underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and pelvic lymphadenectomy and our follow-up indicated that the patients were still free of any disease. Subsequently, a literature review was performed and the results demonstrated that early diagnosis, clinical stage and surgical protocols are the main factors affecting the prognosis of MDA. Close follow-up of the cases may provide more information regarding this disease and the efficacy of the available therapeutic methods. D.A. Spandidos 2013-09 2013-07-08 /pmc/articles/PMC3916131/ /pubmed/24649256 http://dx.doi.org/10.3892/mco.2013.144 Text en Copyright © 2013, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
GUO, FEIFEI
HU, YALI
XU, XIAOFENG
LI, RONG
RU, TONG
WANG, JINGMEI
ZHOU, HUAIJUN
Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature
title Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature
title_full Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature
title_fullStr Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature
title_full_unstemmed Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature
title_short Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature
title_sort diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: a report of two cases and review of the literature
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916131/
https://www.ncbi.nlm.nih.gov/pubmed/24649256
http://dx.doi.org/10.3892/mco.2013.144
work_keys_str_mv AT guofeifei diagnosticchallengesinminimaldeviationadenocarcinomaoftheuterinecervixareportoftwocasesandreviewoftheliterature
AT huyali diagnosticchallengesinminimaldeviationadenocarcinomaoftheuterinecervixareportoftwocasesandreviewoftheliterature
AT xuxiaofeng diagnosticchallengesinminimaldeviationadenocarcinomaoftheuterinecervixareportoftwocasesandreviewoftheliterature
AT lirong diagnosticchallengesinminimaldeviationadenocarcinomaoftheuterinecervixareportoftwocasesandreviewoftheliterature
AT rutong diagnosticchallengesinminimaldeviationadenocarcinomaoftheuterinecervixareportoftwocasesandreviewoftheliterature
AT wangjingmei diagnosticchallengesinminimaldeviationadenocarcinomaoftheuterinecervixareportoftwocasesandreviewoftheliterature
AT zhouhuaijun diagnosticchallengesinminimaldeviationadenocarcinomaoftheuterinecervixareportoftwocasesandreviewoftheliterature