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Overexpression of Heat Shock Protein 72 Attenuates NF-κB Activation Using a Combination of Regulatory Mechanisms in Microglia
Overexpression of the inducible heat shock protein 70, Hsp72, has broadly cytoprotective effects and improves outcome following stroke. A full understanding of how Hsp72 protects cells against injury is elusive, though several distinct mechanisms are implicated. One mechanism is its anti-inflammator...
Autores principales: | Sheppard, Patrick W., Sun, Xiaoyun, Khammash, Mustafa, Giffard, Rona G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916226/ https://www.ncbi.nlm.nih.gov/pubmed/24516376 http://dx.doi.org/10.1371/journal.pcbi.1003471 |
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