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Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Drift on Gene Function

Although two related species may have extremely similar phenotypes, the genetic networks underpinning this conserved biology may have diverged substantially since they last shared a common ancestor. This is termed Developmental System Drift (DSD) and reflects the plasticity of genetic networks. One...

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Detalles Bibliográficos
Autores principales: Verster, Adrian J., Ramani, Arun K., McKay, Sheldon J., Fraser, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916228/
https://www.ncbi.nlm.nih.gov/pubmed/24516395
http://dx.doi.org/10.1371/journal.pgen.1004077