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Mechanistically Distinct Mouse Models for CRX-Associated Retinopathy

Cone-rod homeobox (CRX) protein is a “paired-like” homeodomain transcription factor that is essential for regulating rod and cone photoreceptor transcription. Mutations in human CRX are associated with the dominant retinopathies Retinitis Pigmentosa (RP), Cone-Rod Dystrophy (CoRD) and Leber Congenit...

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Detalles Bibliográficos
Autores principales: Tran, Nicholas M., Zhang, Alan, Zhang, Xiaodong, Huecker, Julie B., Hennig, Anne K., Chen, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916252/
https://www.ncbi.nlm.nih.gov/pubmed/24516401
http://dx.doi.org/10.1371/journal.pgen.1004111