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Generation of a monoclonal antibody against the glycosylphosphatidylinositol-linked protein Rae-1 using genetically engineered tumor cells

BACKGROUND: Although genetically engineered cells have been used to generate monoclonal antibodies (mAbs) against numerous proteins, no study has used them to generate mAbs against glycosylphosphatidylinositol (GPI)-anchored proteins. The GPI-linked protein Rae-1, an NKG2D ligand member, is responsi...

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Detalles Bibliográficos
Autores principales: Hu, Jiemiao, Vien, Long T, Xia, Xueqing, Bover, Laura, Li, Shulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916315/
https://www.ncbi.nlm.nih.gov/pubmed/24495546
http://dx.doi.org/10.1186/1480-9222-16-3

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