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Non-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular Matrix
A key feature of Mycobacterium tuberculosis is its ability to become dormant in the host. Little is known of the mechanisms by which these bacilli are able to persist in this state. Therefore, the focus of this study was to emulate environmental conditions encountered by M. tuberculosis in the granu...
Autores principales: | Bacon, Joanna, Alderwick, Luke J., Allnutt, Jon A., Gabasova, Evelina, Watson, Robert, Hatch, Kim A., Clark, Simon O., Jeeves, Rose E., Marriott, Alice, Rayner, Emma, Tolley, Howard, Pearson, Geoff, Hall, Graham, Besra, Gurdyal S., Wernisch, Lorenz, Williams, Ann, Marsh, Philip D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916317/ https://www.ncbi.nlm.nih.gov/pubmed/24516549 http://dx.doi.org/10.1371/journal.pone.0087329 |
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