EMT and Acquisition of Stem Cell-Like Properties Are Involved in Spontaneous Formation of Tumorigenic Hybrids between Lung Cancer and Bone Marrow-Derived Mesenchymal Stem Cells

The most deadly phase in cancer progression is metastatic conversion. Epithelial-to-mesenchymal transition (EMT) is a key process by which cancer cells acquire invasive and metastatic phenotypes. In order to spawn macroscopic metastases, disseminated cancer cells would seem to require self-renewal c...

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Detalles Bibliográficos
Autores principales: Xu, Mei-Hua, Gao, Xuan, Luo, Dan, Zhou, Xiang-Dong, Xiong, Wei, Liu, Guo-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916343/
https://www.ncbi.nlm.nih.gov/pubmed/24516569
http://dx.doi.org/10.1371/journal.pone.0087893

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