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Evidence of Gene−Environment Interaction for Two Genes on Chromosome 4 and Environmental Tobacco Smoke in Controlling the Risk of Nonsyndromic Cleft Palate
Nonsyndromic cleft palate (CP) is one of the most common human birth defects and both genetic and environmental risk factors contribute to its etiology. We conducted a genome-wide association study (GWAS) using 550 CP case-parent trios ascertained in an international consortium. Stratified analysis...
Autores principales: | Wu, Tao, Schwender, Holger, Ruczinski, Ingo, Murray, Jeffrey C., Marazita, Mary L., Munger, Ronald G., Hetmanski, Jacqueline B., Parker, Margaret M., Wang, Ping, Murray, Tanda, Taub, Margaret, Li, Shuai, Redett, Richard J., Fallin, M. Daniele, Liang, Kung Yee, Wu-Chou, Yah Huei, Chong, Samuel S., Yeow, Vincent, Ye, Xiaoqian, Wang, Hong, Huang, Shangzhi, Jabs, Ethylin W., Shi, Bing, Wilcox, Allen J., Jee, Sun Ha, Scott, Alan F., Beaty, Terri H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916361/ https://www.ncbi.nlm.nih.gov/pubmed/24516586 http://dx.doi.org/10.1371/journal.pone.0088088 |
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