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Shigella Type III Secretion Protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation Independently of Pkcδ

Recognition of intracellular pathogenic bacteria by members of the nucleotide-binding domain and leucine-rich repeat containing (NLR) family triggers immune responses against bacterial infection. A major response induced by several Gram-negative bacteria is the activation of caspase-1 via the Nlrc4...

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Detalles Bibliográficos
Autores principales:	Suzuki, Shiho, Franchi, Luigi, He, Yuan, Muñoz-Planillo, Raul, Mimuro, Hitomi, Suzuki, Toshihiko, Sasakawa, Chihiro, Núñez, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916413/ https://www.ncbi.nlm.nih.gov/pubmed/24516390 http://dx.doi.org/10.1371/journal.ppat.1003926

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