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Lundep, a Sand Fly Salivary Endonuclease Increases Leishmania Parasite Survival in Neutrophils and Inhibits XIIa Contact Activation in Human Plasma

Neutrophils are the host's first line of defense against infections, and their extracellular traps (NET) were recently shown to kill Leishmania parasites. Here we report a NET-destroying molecule (Lundep) from the salivary glands of Lutzomyia longipalpis. Previous analysis of the sialotranscrip...

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Detalles Bibliográficos
Autores principales:	Chagas, Andrezza C., Oliveira, Fabiano, Debrabant, Alain, Valenzuela, Jesus G., Ribeiro, José M. C., Calvo, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916414/ https://www.ncbi.nlm.nih.gov/pubmed/24516388 http://dx.doi.org/10.1371/journal.ppat.1003923

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