Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging

Dietary restriction extends longevity in organisms ranging from bacteria to mice and protects primates from a variety of diseases, but the contribution of each dietary component to aging is poorly understood. Here we demonstrate that glucose and specific amino acids promote stress sensitization and...

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Detalles Bibliográficos
Autores principales: Mirisola, Mario G., Taormina, Giusi, Fabrizio, Paola, Wei, Min, Hu, Jia, Longo, Valter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916422/
https://www.ncbi.nlm.nih.gov/pubmed/24516402
http://dx.doi.org/10.1371/journal.pgen.1004113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916422/
https://www.ncbi.nlm.nih.gov/pubmed/24516402
http://dx.doi.org/10.1371/journal.pgen.1004113

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