Cargando…

Development and Validation of a Chemostat Gut Model To Study Both Planktonic and Biofilm Modes of Growth of Clostridium difficile and Human Microbiota

The human gastrointestinal tract harbours a complex microbial community which exist in planktonic and sessile form. The degree to which composition and function of faecal and mucosal microbiota differ remains unclear. We describe the development and characterisation of an in vitro human gut model, w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crowther, Grace S., Chilton, Caroline H., Todhunter, Sharie L., Nicholson, Scott, Freeman, Jane, Baines, Simon D., Wilcox, Mark H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916432/ https://www.ncbi.nlm.nih.gov/pubmed/24516647 http://dx.doi.org/10.1371/journal.pone.0088396

Ejemplares similares

SMT19969 as a treatment for Clostridium difficile infection: an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model
por: Baines, S. D., et al.
Publicado: (2015)

In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile
por: Corbett, D., et al.
Publicado: (2015)

Antibiotic therapy and Clostridium difficile infection – primum non nocere – first do no harm
por: Crowther, Grace S, et al.
Publicado: (2015)

Potential of lactoferrin to prevent antibiotic-induced Clostridium difficile infection
por: Chilton, C. H., et al.
Publicado: (2016)

Antimicrobial Resistance and Reduced Susceptibility in Clostridium difficile: Potential Consequences for Induction, Treatment, and Recurrence of C. difficile Infection
por: Baines, Simon D., et al.
Publicado: (2015)

Omadacycline Gut Microbiome Exposure Does Not Induce Clostridium difficile Proliferation or Toxin Production in a Model That Simulates the Proximal, Medial, and Distal Human Colon
por: Moura, Ines B., et al.
Publicado: (2019)

Role of cephalosporins in the era of Clostridium difficile infection
por: Wilcox, Mark H., et al.
Publicado: (2017)

Specialized activities and expression differences for Clostridium thermocellum biofilm and planktonic cells
por: Dumitrache, Alexandru, et al.
Publicado: (2017)

Five-year Pan-European, longitudinal surveillance of Clostridium difficile ribotype prevalence and antimicrobial resistance: the extended ClosER study
por: Freeman, Jane, et al.
Publicado: (2019)

The efficacy of thuricin CD, tigecycline, vancomycin, teicoplanin, rifampicin and nitazoxanide, independently and in paired combinations against Clostridium difficile biofilms and planktonic cells
por: Mathur, Harsh, et al.
Publicado: (2016)

The Clostridium difficile Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties
por: Pantaléon, Véronique, et al.
Publicado: (2015)

Method comparison for the direct enumeration of bacterial species using a chemostat model of the human colon
por: Moura, Ines B., et al.
Publicado: (2020)

MBRA-2: a Modified Chemostat System to Culture Biofilms
por: Jens, Justin N., et al.
Publicado: (2022)

Association of Fidaxomicin with C. difficile Spores: Effects of Persistence on Subsequent Spore Recovery, Outgrowth and Toxin Production
por: Chilton, Caroline H., et al.
Publicado: (2016)

Metabolic Fluxes of Nitrogen and Pyrophosphate in Chemostat Cultures of Clostridium thermocellum and Thermoanaerobacterium saccharolyticum
por: Holwerda, Evert K., et al.
Publicado: (2020)

Short-Term Genome Stability of Serial Clostridium difficile Ribotype 027 Isolates in an Experimental Gut Model and Recurrent Human Disease
por: Eyre, David W., et al.
Publicado: (2013)

Biofilm formation of Clostridium difficile and susceptibility to Manuka Honey
por: Hammond, Eric N, et al.
Publicado: (2014)

Spore Formation and Toxin Production in Clostridium difficile Biofilms
por: Semenyuk, Ekaterina G., et al.
Publicado: (2014)

Susceptibility of Clostridium difficile Isolates of Varying Antimicrobial Resistance Phenotypes to SMT19969 and 11 Comparators
por: Freeman, Jane, et al.
Publicado: (2015)

C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth
por: Chua, Song Lin, et al.
Publicado: (2015)

A Review of Mixed Strain Clostridium difficile Colonization and Infection
por: Dayananda, Pete, et al.
Publicado: (2019)

Tragedy of the commons in the chemostat
por: Schuster, Martin, et al.
Publicado: (2017)

A microbiota-generated bile salt induces biofilm formation in Clostridium difficile
por: Dubois, Thomas, et al.
Publicado: (2019)

2407. Overexpression of Virulence Factors in Biofilm from Recurrent Clostridium (Clostridioides) difficile Infection Isolates.
por: Tijerina, Laura, et al.
Publicado: (2019)

In Vitro Activities of MCB3681 and Eight Comparators against Clostridium difficile Isolates with Known Ribotypes and Diverse Geographical Spread
por: Freeman, Jane, et al.
Publicado: (2017)

Characterisation of Clostridium difficile Biofilm Formation, a Role for Spo0A
por: Dawson, Lisa F., et al.
Publicado: (2012)

Clostridium: Transmission difficile?
por: Harbarth, Stephan, et al.
Publicado: (2012)

An Analysis of Clostridium difficile Environmental Contamination During and After Treatment for C difficile Infection
por: Davies, Kerrie, et al.
Publicado: (2020)

Succinic acid production with Actinobacillus succinogenes: rate and yield analysis of chemostat and biofilm cultures
por: Brink, Hendrik Gideon, et al.
Publicado: (2014)

Growth, Viability, and Death of Planktonic and Biofilm Sphingomonas desiccabilis in Simulated Martian Brines
por: Stevens, Adam H., et al.
Publicado: (2019)

Diverse Temperate Bacteriophage Carriage in Clostridium difficile 027 Strains
por: Nale, Janet Y., et al.
Publicado: (2012)

Efficacy of carvacrol against resistant rapidly growing mycobacteria in the planktonic and biofilm growth mode
por: Marini, Emanuela, et al.
Publicado: (2019)

Variability in testing policies and impact on reported Clostridium difficile infection rates: results from the pilot Longitudinal European Clostridium difficile Infection Diagnosis surveillance study (LuCID)
por: Davies, K., et al.
Publicado: (2016)

High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection
por: Monaghan, Tanya M, et al.
Publicado: (2017)

Evolutionary History of the Clostridium difficile Pathogenicity Locus
por: Dingle, Kate E., et al.
Publicado: (2013)

Etiology of Infectious Diarrhea in Patients Tested for Clostridium difficile: If It Isn’t Clostridium difficile, What Is It?
por: Kwon, Jennie H, et al.
Publicado: (2017)

A proteomic and transcriptional view of acidogenic and solventogenic steady-state cells of Clostridium acetobutylicum in a chemostat culture
por: Janssen, Holger, et al.
Publicado: (2010)

Biofilm Structures in a Mono-Associated Mouse Model of Clostridium difficile Infection
por: Soavelomandroso, Anna P., et al.
Publicado: (2017)

Hash-Based Core Genome Multilocus Sequence Typing for Clostridium difficile
por: Eyre, David W., et al.
Publicado: (2019)

Evaluation of the Xpert Clostridium difficile Assay for the Diagnosis of Clostridium difficile Infection
por: Shin, Saeam, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_barul0dl86bqaipprpau0fgeio