Clostridium difficile Infection: A Worldwide Disease

Clostridium difficile, an anaerobic toxigenic bacterium, causes a severe infectious colitis that leads to significant morbidity and mortality worldwide. Both enhanced bacterial toxins and diminished host immune response contribute to symptomatic disease. C. difficile has been a well-established path...

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Detalles Bibliográficos
Autores principales: Burke, Kristin E., Lamont, J. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916678/
https://www.ncbi.nlm.nih.gov/pubmed/24516694
http://dx.doi.org/10.5009/gnl.2014.8.1.1
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author Burke, Kristin E.
Lamont, J. Thomas
author_facet Burke, Kristin E.
Lamont, J. Thomas
author_sort Burke, Kristin E.
collection PubMed
description Clostridium difficile, an anaerobic toxigenic bacterium, causes a severe infectious colitis that leads to significant morbidity and mortality worldwide. Both enhanced bacterial toxins and diminished host immune response contribute to symptomatic disease. C. difficile has been a well-established pathogen in North America and Europe for decades, but is just emerging in Asia. This article reviews the epidemiology, microbiology, pathophysiology, and clinical management of C. difficile. Prompt recognition of C. difficile is necessary to implement appropriate infection control practices.
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spelling pubmed-39166782014-02-10 Clostridium difficile Infection: A Worldwide Disease Burke, Kristin E. Lamont, J. Thomas Gut Liver Review Clostridium difficile, an anaerobic toxigenic bacterium, causes a severe infectious colitis that leads to significant morbidity and mortality worldwide. Both enhanced bacterial toxins and diminished host immune response contribute to symptomatic disease. C. difficile has been a well-established pathogen in North America and Europe for decades, but is just emerging in Asia. This article reviews the epidemiology, microbiology, pathophysiology, and clinical management of C. difficile. Prompt recognition of C. difficile is necessary to implement appropriate infection control practices. The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2014-01 2014-01-13 /pmc/articles/PMC3916678/ /pubmed/24516694 http://dx.doi.org/10.5009/gnl.2014.8.1.1 Text en Copyright © 2014 by the Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Burke, Kristin E.
Lamont, J. Thomas
Clostridium difficile Infection: A Worldwide Disease
title Clostridium difficile Infection: A Worldwide Disease
title_full Clostridium difficile Infection: A Worldwide Disease
title_fullStr Clostridium difficile Infection: A Worldwide Disease
title_full_unstemmed Clostridium difficile Infection: A Worldwide Disease
title_short Clostridium difficile Infection: A Worldwide Disease
title_sort clostridium difficile infection: a worldwide disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916678/
https://www.ncbi.nlm.nih.gov/pubmed/24516694
http://dx.doi.org/10.5009/gnl.2014.8.1.1
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