Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature

Hemolytic uremic syndrome (HUS) is a rare thrombotic complication characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. HUS may be caused by several different conditions, including infection, malignancy, and chemotherapeutic agents, such as mitomyc...

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Autores principales: Lee, Hye Won, Chung, Moon Jae, Kang, Huapyong, Choi, Heun, Choi, Youn Jeong, Lee, Kyung Joo, Lee, Seung Woo, Han, Seung Hyuk, Kim, Jin Seok, Song, Si Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916680/
https://www.ncbi.nlm.nih.gov/pubmed/24516709
http://dx.doi.org/10.5009/gnl.2014.8.1.109
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author Lee, Hye Won
Chung, Moon Jae
Kang, Huapyong
Choi, Heun
Choi, Youn Jeong
Lee, Kyung Joo
Lee, Seung Woo
Han, Seung Hyuk
Kim, Jin Seok
Song, Si Young
author_facet Lee, Hye Won
Chung, Moon Jae
Kang, Huapyong
Choi, Heun
Choi, Youn Jeong
Lee, Kyung Joo
Lee, Seung Woo
Han, Seung Hyuk
Kim, Jin Seok
Song, Si Young
author_sort Lee, Hye Won
collection PubMed
description Hemolytic uremic syndrome (HUS) is a rare thrombotic complication characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. HUS may be caused by several different conditions, including infection, malignancy, and chemotherapeutic agents, such as mitomycin, cisplatin, and most recently, gemcitabine. The outcome of gemcitabine-induced HUS is poor, and the disease has a high mortality rate. This study reports a case of gemcitabine-induced HUS in a patient with pancreatic cancer in Korea.
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spelling pubmed-39166802014-02-10 Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature Lee, Hye Won Chung, Moon Jae Kang, Huapyong Choi, Heun Choi, Youn Jeong Lee, Kyung Joo Lee, Seung Woo Han, Seung Hyuk Kim, Jin Seok Song, Si Young Gut Liver Case Report Hemolytic uremic syndrome (HUS) is a rare thrombotic complication characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. HUS may be caused by several different conditions, including infection, malignancy, and chemotherapeutic agents, such as mitomycin, cisplatin, and most recently, gemcitabine. The outcome of gemcitabine-induced HUS is poor, and the disease has a high mortality rate. This study reports a case of gemcitabine-induced HUS in a patient with pancreatic cancer in Korea. The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2014-01 2014-01-13 /pmc/articles/PMC3916680/ /pubmed/24516709 http://dx.doi.org/10.5009/gnl.2014.8.1.109 Text en Copyright © 2014 by the Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Hye Won
Chung, Moon Jae
Kang, Huapyong
Choi, Heun
Choi, Youn Jeong
Lee, Kyung Joo
Lee, Seung Woo
Han, Seung Hyuk
Kim, Jin Seok
Song, Si Young
Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature
title Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature
title_full Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature
title_fullStr Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature
title_full_unstemmed Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature
title_short Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature
title_sort gemcitabine-induced hemolytic uremic syndrome in pancreatic cancer: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916680/
https://www.ncbi.nlm.nih.gov/pubmed/24516709
http://dx.doi.org/10.5009/gnl.2014.8.1.109
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