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Recent Advances and Uses of Grape Flavonoids as Nutraceuticals
Grape is one of the oldest fruit crops domesticated by humans. The numerous uses of grape in making wine, beverages, jelly, and other products, has made it one of the most economically important plants worldwide. The complex phytochemistry of the berry is characterized by a wide variety of compounds...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916869/ https://www.ncbi.nlm.nih.gov/pubmed/24451310 http://dx.doi.org/10.3390/nu6010391 |
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author | Georgiev, Vasil Ananga, Anthony Tsolova, Violeta |
author_facet | Georgiev, Vasil Ananga, Anthony Tsolova, Violeta |
author_sort | Georgiev, Vasil |
collection | PubMed |
description | Grape is one of the oldest fruit crops domesticated by humans. The numerous uses of grape in making wine, beverages, jelly, and other products, has made it one of the most economically important plants worldwide. The complex phytochemistry of the berry is characterized by a wide variety of compounds, most of which have been demonstrated to have therapeutic or health promoting properties. Among them, flavonoids are the most abundant and widely studied, and have enjoyed greater attention among grape researchers in the last century. Recent studies have shown that the beneficial health effects promoted by consumption of grape and grape products are attributed to the unique mix of polyphenolic compounds. As the largest group of grape polyphenols, flavonoids are the main candidates considered to have biological properties, including but not limited to antioxidant, anti-inflammatory, anti-cancer, antimicrobial, antiviral, cardioprotective, neuroprotective, and hepatoprotective activities. Here, we discuss the recent scientific advances supporting the beneficial health qualities of grape and grape-derived products, mechanisms of their biological activity, bioavailability, and their uses as nutraceuticals. The advantages of modern plant cell based biotechnology as an alternative method for production of grape nutraceuticals and improvement of their health qualities are also discussed. |
format | Online Article Text |
id | pubmed-3916869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-39168692014-02-07 Recent Advances and Uses of Grape Flavonoids as Nutraceuticals Georgiev, Vasil Ananga, Anthony Tsolova, Violeta Nutrients Review Grape is one of the oldest fruit crops domesticated by humans. The numerous uses of grape in making wine, beverages, jelly, and other products, has made it one of the most economically important plants worldwide. The complex phytochemistry of the berry is characterized by a wide variety of compounds, most of which have been demonstrated to have therapeutic or health promoting properties. Among them, flavonoids are the most abundant and widely studied, and have enjoyed greater attention among grape researchers in the last century. Recent studies have shown that the beneficial health effects promoted by consumption of grape and grape products are attributed to the unique mix of polyphenolic compounds. As the largest group of grape polyphenols, flavonoids are the main candidates considered to have biological properties, including but not limited to antioxidant, anti-inflammatory, anti-cancer, antimicrobial, antiviral, cardioprotective, neuroprotective, and hepatoprotective activities. Here, we discuss the recent scientific advances supporting the beneficial health qualities of grape and grape-derived products, mechanisms of their biological activity, bioavailability, and their uses as nutraceuticals. The advantages of modern plant cell based biotechnology as an alternative method for production of grape nutraceuticals and improvement of their health qualities are also discussed. MDPI 2014-01-21 /pmc/articles/PMC3916869/ /pubmed/24451310 http://dx.doi.org/10.3390/nu6010391 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Georgiev, Vasil Ananga, Anthony Tsolova, Violeta Recent Advances and Uses of Grape Flavonoids as Nutraceuticals |
title | Recent Advances and Uses of Grape Flavonoids as Nutraceuticals |
title_full | Recent Advances and Uses of Grape Flavonoids as Nutraceuticals |
title_fullStr | Recent Advances and Uses of Grape Flavonoids as Nutraceuticals |
title_full_unstemmed | Recent Advances and Uses of Grape Flavonoids as Nutraceuticals |
title_short | Recent Advances and Uses of Grape Flavonoids as Nutraceuticals |
title_sort | recent advances and uses of grape flavonoids as nutraceuticals |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916869/ https://www.ncbi.nlm.nih.gov/pubmed/24451310 http://dx.doi.org/10.3390/nu6010391 |
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