CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism

The search for genes with a positive influence on physical fitness is a difficult process. Physical fitness is a trait determined by multiple genes, and its genetic basis is then modified by numerous environmental factors. The present study examines the effects of the polymorphism of creatine kinase...

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Autores principales: Gronek, Piotr, Holdys, Joanna, Kryściak, Jakub, Stanisławski, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Akademia Wychowania Fizycznego w Katowicach 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916923/
https://www.ncbi.nlm.nih.gov/pubmed/24511349
http://dx.doi.org/10.2478/hukin-2013-0076
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author Gronek, Piotr
Holdys, Joanna
Kryściak, Jakub
Stanisławski, Daniel
author_facet Gronek, Piotr
Holdys, Joanna
Kryściak, Jakub
Stanisławski, Daniel
author_sort Gronek, Piotr
collection PubMed
description The search for genes with a positive influence on physical fitness is a difficult process. Physical fitness is a trait determined by multiple genes, and its genetic basis is then modified by numerous environmental factors. The present study examines the effects of the polymorphism of creatine kinase (CKM) gene on VO2max – a physiological index of aerobic capacity of high heritability. The study sample consisted of 154 men and 85 women, who were students of the University School of Physical Education in Poznań and athletes practicing various sports, including members of the Polish national team. The study revealed a positive effect of a rare G (NcoI−) allele of the CKM gene on maximal oxygen uptake in Caucasian women practicing sports requiring aerobic and anaerobic exercise metabolism. Also a tendency was noted in individuals with NcoI−/− (GG) and NcoI−/+ (GA) genotypes to reach higher VO2max levels.
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spelling pubmed-39169232014-02-07 CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism Gronek, Piotr Holdys, Joanna Kryściak, Jakub Stanisławski, Daniel J Hum Kinet Research Article The search for genes with a positive influence on physical fitness is a difficult process. Physical fitness is a trait determined by multiple genes, and its genetic basis is then modified by numerous environmental factors. The present study examines the effects of the polymorphism of creatine kinase (CKM) gene on VO2max – a physiological index of aerobic capacity of high heritability. The study sample consisted of 154 men and 85 women, who were students of the University School of Physical Education in Poznań and athletes practicing various sports, including members of the Polish national team. The study revealed a positive effect of a rare G (NcoI−) allele of the CKM gene on maximal oxygen uptake in Caucasian women practicing sports requiring aerobic and anaerobic exercise metabolism. Also a tendency was noted in individuals with NcoI−/− (GG) and NcoI−/+ (GA) genotypes to reach higher VO2max levels. Akademia Wychowania Fizycznego w Katowicach 2013-12-31 /pmc/articles/PMC3916923/ /pubmed/24511349 http://dx.doi.org/10.2478/hukin-2013-0076 Text en © Editorial Committee of Journal of Human Kinetics This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Research Article
Gronek, Piotr
Holdys, Joanna
Kryściak, Jakub
Stanisławski, Daniel
CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism
title CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism
title_full CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism
title_fullStr CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism
title_full_unstemmed CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism
title_short CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism
title_sort ckm gene g (ncoi-) allele has a positive effect on maximal oxygen uptake in caucasian women practicing sports requiring aerobic and anaerobic exercise metabolism
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916923/
https://www.ncbi.nlm.nih.gov/pubmed/24511349
http://dx.doi.org/10.2478/hukin-2013-0076
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