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Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis

In the present study we provide evidence that solomonsterol A, a selective pregnane X receptor (PXR) agonist isolated from the marine sponge Theonella swinhoei, exerts anti-inflammatory activity and attenuates systemic inflammation and immune dysfunction in a mouse model of rheumatoid arthritis. Sol...

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Detalles Bibliográficos
Autores principales:	Mencarelli, Andrea, D’Amore, Claudio, Renga, Barbara, Cipriani, Sabrina, Carino, Adriana, Sepe, Valentina, Perissutti, Elisa, D’Auria, Maria Valeria, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917259/ https://www.ncbi.nlm.nih.gov/pubmed/24368568 http://dx.doi.org/10.3390/md12010036

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