Discovery of Novel Diterpenoids from Sinularia arborea

Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Hua, Dai, Chang-Feng, Hwang, Tsong-Long, Chen, Chun-Yu, Li, Jan-Jung, Chen, Jih-Jung, Wu, Yang-Chang, Sheu, Jyh-Horng, Wang, Wei-Hsien, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917279/
https://www.ncbi.nlm.nih.gov/pubmed/24445307
http://dx.doi.org/10.3390/md12010385
Descripción
Sumario:Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.

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