Identification and Biochemical Characterization of Halisulfate 3 and Suvanine as Novel Inhibitors of Hepatitis C Virus NS3 Helicase from a Marine Sponge

Hepatitis C virus (HCV) is an important etiological agent that is responsible for the development of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. HCV nonstructural protein 3 (NS3) helicase is a possible target for novel drug development due to its essential role in viral replica...

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Detalles Bibliográficos
Autores principales: Furuta, Atsushi, Abdus Salam, Kazi, Hermawan, Idam, Akimitsu, Nobuyoshi, Tanaka, Junichi, Tani, Hidenori, Yamashita, Atsuya, Moriishi, Kohji, Nakakoshi, Masamichi, Tsubuki, Masayoshi, Peng, Poh Wee, Suzuki, Youichi, Yamamoto, Naoki, Sekiguchi, Yuji, Tsuneda, Satoshi, Noda, Naohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917281/
https://www.ncbi.nlm.nih.gov/pubmed/24451189
http://dx.doi.org/10.3390/md12010462

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