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Ion channels and transporters in the development of drug resistance in cancer cells

Multi-drug resistance (MDR) to chemotherapy is the major challenge in the treatment of cancer. MDR can develop by numerous mechanisms including decreased drug uptake, increased drug efflux and the failure to undergo drug-induced apoptosis. Evasion of drug-induced apoptosis through modulation of ion...

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Detalles Bibliográficos
Autores principales: Hoffmann, Else K., Lambert, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917363/
https://www.ncbi.nlm.nih.gov/pubmed/24493757
http://dx.doi.org/10.1098/rstb.2013.0109

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