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Role of LET and chromatin structure on chromosomal inversion in CHO10B2 cells

BACKGROUND: In this study we evaluated the effect of linear energy transfer (LET) and chromatin structure on the induction of chromosomal inversion. High LET radiation causes more complex DNA damage than low LET radiation; this “dirty” damage is more difficult to repair and may result in an increase...

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Detalles Bibliográficos
Autores principales: Cartwright, Ian M, Genet, Matthew D, Fujimori, Akira, Kato, Takamitsu A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917374/
https://www.ncbi.nlm.nih.gov/pubmed/24467838
http://dx.doi.org/10.1186/2041-9414-5-1